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Pediatric Epilepsy Surgery

Pediatric Epilepsy Surgery

Preoperative Assessment and Surgical Treatment


Format: Hardback
ISBN: 9781626238169
Publication Date: September 2019

Please note that payment will be taken immediately. The book will be delivered to you when it is in stock, as per the publication date.

The definitive guide to surgical management of epilepsy in pediatric patients

This fully revised and updated second edition of Pediatric Epilepsy Surgery, edited by internationally renowned pediatric neurosurgeons and epilepsy surgery experts Oğuz Çataltepe and George Jallo, fills a void in the literature, encompassing the full spectrum of topics related to the surgical treatment of intractable epilepsy and seizures in children. The prodigiously illustrated book and its accompanying videos feature contributions from distinguished specialists in several different countries across a wide range of disciplines.

From epidemiology, genetics, pathology, preoperative electrophysiological assessment and neuroimaging to state-of-the-art surgical approaches, this remarkable resource covers the full depth and breadth of surgical management of pediatric epilepsy. Topics include awake anesthesia, intracranial stimulation and mapping techniques, temporal and extratemporal epilepsy surgery techniques, insular, multilobar and hemispheric surgery approaches, and diverse disconnection, neuromodulation, and ablative procedures. Insights are provided on postoperative issues including seizure control, neuropsychological and psychosocial outcomes, surgical failure and re-operation, and much more.

Key Features

  • A review of topographic anatomy of the cerebral cortex and white matter with numerous illustrations provides enhanced understanding of eloquent anatomy.
  • Discussion of cutting-edge techniques such as stereo-electroencephalography, multi-modality imaging and tractography, endoscopic and laser ablation approaches in hypothalamic hamartomas, peri-insular quadrantotomy, and various hemispherotomy approaches.
  • Overview of common cortical stimulation and mapping techniques including magnetic and electrical stimulation modalities, functional MRI, and the WADA test.
  • 13 videos demonstrate seizure semiology, stimulation, awake surgery, hemispherotomy, amygdalohippocampectomy, and endoscopic corpus callosotomy.

This state-of-the-art resource is a must-have for epilepsy surgeons and epileptologists. It will also greatly benefit neurosurgeons, neurologists, clinical neuropsychologists, electrophysiologists, neuroradiologists, residents, fellows, and medical students involved in the assessment and surgical management of epilepsy in pediatric patients.

This book includes complimentary access to a digital copy on

Part I. Introduction to Epilepsy in Children
Chapter 1: Basic Considerations of Pediatric Epilepsy Surgery
Chapter 2: A Historical Review of Epilepsy Surgery and Its Application in Children
Chapter 3: Epidemiology of Intractable Epilepsy in Children
Chapter 4: Genetics in Epilepsy Surgery
Chapter 5: Surgical Neuropathology of Pediatric Epilepsy
Chapter 6: Epilepsy and Brain Plasticity
Chapter 7: Effects of Seizures and Their Comorbidities on the Developing Brain
Chapter 8: Ethical Considerations in Pediatric Epilepsy Surgery
Chapter 9: Infantile and Childhood-Onset Catastrophic Epilepsy Syndromes
Chapter 10: Epilepsy Surgery for Congenital or Early Brain Lesions
Part II. Preoperative Assessment
Section IIa. Preoperative Clinical and Neuropsychological Assessment
Chapter 11: Intractable Epilepsy in Children and Selection of Surgical Candidates
Chapter 12: Clinical Semiology in Preoperative Assessment
Chapter 13: Preoperative Neuropsychological and Cognitive Assessment
Section IIb. Preoperative Electrophysiological Assessment
Chapter 14: Electroencephalography and Noninvasive Electrophysiological Assessment
Chapter 15: Invasive Electrophysiological Monitoring
Chapter 16: Extra- and Intraoperative Electrocortical Stimulation
Chapter 17: Stereo-Electroencephalography
Chapter 18: Magnetoencephalography
Section IIc. Preoperative Neuroimaging
Chapter 19: Structural Brain Imaging in Pediatric Epilepsy
Chapter 20: Functional Magnetic Resonance Imaging in Pediatric Epilepsy Surgery
Chapter 21: Application of Positron Emission Tomography and Single-Photon Emission Computed Tomography in Pediatric Epilepsy Surgery
Chapter 22: Multimodality Imaging and Coregistration
Part III. Surgical Anatomy and Mapping Techniques
Chapter 23: Embryological Development and Topographical Anatomy of the Cerebral Cortex
Chapter 24: Tractographic Anatomy of White Matter
Chapter 25: Localization of Motor Cortex and Subcortical Pathways Using Functional Magnetic Resonance Imaging and Diffusion Tensor Imaging
Chapter 26: The Wada Test: Lateralization of Language and Memory
Chapter 27: Language Lateralization and Localization: Functional Magnetic Resonance Imaging
Chapter 28: Localization of Eloquent Cortex and White Matter Tracts Under General Anesthesia
Chapter 29: Cortical Stimulation and Mapping
Chapter 30: Subcortical Mapping During Intracranial Surgery in Children
Part IV. Surgical Treatment of Epilepsy
Section IVa. Anesthesia
Chapter 31: Anesthetic Considerations and Postoperative ICU Care in Pediatric Epilepsy Surgery
Chapter 32: Pediatric Awake Craniotomy
Section IVb. Intracranial Electrode Placement for Invasive Monitoring
Chapter 33: Implantation of Strip, Grid, and Depth Electrodes for Invasive Electrophysiological Monitoring
Chapter 34: Stereo-Electroencephalography in Children: Methodology and Surgical Technique
Section IVc. Temporal Lobe Epilepsy and Surgical Approaches
Chapter 35: Mesial Temporal Sclerosis in Pediatric Epilepsy
Chapter 36: Anteromesial Temporal Lobectomy
Chapter 37: Selective Amygdalohippocampectomy
Chapter 38: Surgical Management of Lesional Temporal Lobe Epilepsy
Chapter 39: Surgical Management of MRI-Negative Temporal Lobe Epilepsy
Section IVd. Extratemporal Lobe Epilepsy and Surgical Approaches
Chapter 40: Surgical Management of Insular-Opercular Epilepsy in Children
Chapter 41: Focal Cortical Dysplasia: Histopathology, Neuroimaging, and Electro-Clinical Presentation
Chapter 42: Surgical Approaches in Cortical Dysplasia
Chapter 43: Tuberous Sclerosis Complex
Chapter 44: Resective Epilepsy Surgery for Tuberous Sclerosis Complex
Chapter 45: Extratemporal Resection and Staged Epilepsy Surgery in Children
Chapter 46: Supplementary Sensorimotor Area Surgery
Chapter 47: Rolandic Cortex Surgery
Chapter 48: Anterior Peri-Insular Quadrantotomy
Chapter 49: Posterior Peri-Insular Quadrantotomy
Chapter 50: Tailored Extratemporal Resection in Children with Epilepsy
Chapter 51: Surgical Management of MRI-Negative Extratemporal Lobe Epilepsy
Chapter 52: Surgical Management of Hypothalamic Hamartomas
Section IVe. Hemispheric Surgery Techniques
Chapter 53: Hemispherectomy and Hemispherotomy Techniques in Pediatric Epilepsy Surgery
Chapter 54: Multifocal Epilepsy and Multilobar Resections
Chapter 55: Anatomical Hemispherectomy
Chapter 56: Hemidecortication for Intractable Epilepsy
Chapter 57: Functional Hemispherectomy at the University of California, Los Angeles
Chapter 58: Transsylvian Hemispheric Deafferentiation
Chapter 59: Vertical Parasagittal Hemispherotomy
Chapter 60: Peri-Insular Hemispherotomy
Chapter 61: Endoscope-Assisted Hemispherotomy
Section IVf. Other Disconnective Procedures
Chapter 62: Corpus Callosotomy
Chapter 63: Endoscope-Assisted Corpus Callosotomy with Anterior, Hippocampal, and Posterior Commissurotomy
Chapter 64: Endoscopic Disconnection in Hypothalamic Hamartomas
Chapter 65: Multiple Subpial Transections in Children with Refractory Epilepsy
Chapter 66: Hippocampal Subpial Transection
Section IVg. Neuromodulation Procedures
Chapter 67: Vagal Nerve Stimulation
Chapter 68: Cortical and Deep Brain Stimulation
Section IVh. Radiosurgery and Ablative Procedures
Chapter 69: Radiosurgical Treatment for Epilepsy
Chapter 70: Stereotactic Laser Ablation for Hypothalamic Hamartomas
Chapter 71: MRI-Guided Laser Thermal Therapy in Pediatric Epilepsy Surgery
Part V. Postoperative Course and Outcome
Chapter 72: Surgical Failure and Reoperation
Chapter 73: Postoperative Seizure Control
Chapter 74: Postoperative Neuropsychological and Psychosocial Outcome

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