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Cavernous Malformations of the Brain and Spinal Cord

Cavernous Malformations of the Brain and Spinal Cord


Format: Hardback
ISBN: 9781588903433
Publication Date: September 2007

Current techniques for clinical management

This book presents a comprehensive overview of the basic science and current clinical knowledge on cavernous malformations of the brain and spinal cord. Cavernous Malformations of the Brain and Spinal Cord begins by covering general aspects of the disease, including the natural history, molecular biology, pathological processes, genetic basis, neuroradiology, and classification of cavernous malformations. Separate chapters then address the various types of cavernous malformations, thoroughly describing the clinical presentation and management approaches for each clinical situation. Incisive review of recent literature sheds light on topics of incidence, location, and outcomes.

  • Clinical insights regarding indications for surgery, surgical techniques, outcomes, and prognostic factors drawn from the authors' extensive experiences
  • Discussion of treatment of patients with specific disorders, such as epilepsy
  • Coverage of cavernous malformations as dynamic lesions with descriptions of de novo formation and lesions induced by irradiation

Neurosurgeons, neurologists, and neuroradiologists, especially those caring for patients with seizures and hemorrhagic stroke, will benefit from the wealth of information in this complete reference.

Section I General Aspects
1. Natural History of Cavernous Malformations of the Central Nervous System
2. Molecular Biology of Cerebral Cavernous Malformations
3. Pathology of Cerebral Cavernous Malformations
4. Genetics of Cerebral Cavernous Malformations
5. Cavernous Malformations as a Dynamic Lesions: De Novo Formation, Radiological Changes, and Radiation-Induced Forms
6. Systematic Cavernous Malformations
7. Capillary Telangiectasias, Cavernous Malformations, and Developmental Venous Anomalies: Different Expressions of the Same Disease Process?
8. Neuroradiology and Classification of Cavernous Malformations
Section II Clinical Presentations, Indications for Surgery, Surgical Techniques, and Outcomes
9. Supratentorial Cavernous Malformations
10. Deep-Seated Cerebral Cavernous Malformations
11. Brain Stem Cavernous Malformations
12. Cavernous Malformations of the Spinal Cord
13. Giant Cavernous Angiomas of the Cavernous Sinus
14. Management of Atypical Cavernous Malformations
15. Cavernous Malformations and Seizures: Lesionectomy or Epilepsy Surgery?
16. Cavernous Malformations in Children and Adolescents
17. Radiosurgery for Cavernous Malformations

Easily accessible to residents or fellows...This book is an excellent resource that merits inclusion in the core curriculum of training programs, as well as being useful as a reference for others interested in cavernous malformations.--Journal of Neurosurgery

"[This] books belongs in any vascular neurosurgeons bookself and might also be of interest for scientists interested in the biology of cavernous malformations."--Neurosurgical Review 2/10

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